Author(s):
Irem Kulu, Melek Gul, Omer Tahir Gunkara and Nuket OcalPages 409-418 (10)
Abstract:
Our research group has published numerous papers over the last three years on the reaction of nitrile oxides and azomethine ylide with unsaturated tricyclic N-substituted dicarboximides selected according to the importance of possible biological activities. These reactions cover full range of mechanistic pathways and timings of bond-forming processes to give five-membered ring closure by 1,3-dipolar cycloaddition.
Keywords:
Azomethine ylide, biological active molecules, 1, 3-dipolar cycloaddition, hydrazones, isoxazolines, nitrile oxides, tricyclic imides.
Affiliation:
Yildiz Technical University, Faculty of Science and Arts, Davutpasa Campus, 34220 Istanbul, Turkey.
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