M13 Bacteriophage-Based Self-Assembly Structures and Their Functional Capabilities

Author(s):

Jong-Sik Moon, Won-Geun Kim, Chuntae Kim, Geun-Tae Park, Jeong Heo, So Y. Yoo and Jin-Woo OhPages 271-281 (11)

Abstract:

Controlling the assembly of basic structural building blocks in a systematic and orderly fashion is an emerging issue in various areas of science and engineering such as physics, chemistry, material science, biological engineering, and electrical engineering. The self-assembly technique, among many other kinds of ordering techniques, has several unique advantages and the M13 bacteriophage can be utilized as part of this technique. The M13 bacteriophage (Phage) can easily be modified genetically and chemically to demonstrate specific functions. This allows for its use as a template to determine the homogeneous distribution and percolated network structures of inorganic nanostructures under ambient conditions. Inexpensive and environmentally friendly synthesis can be achieved by using the M13 bacteriophage as a novel functional building block. Here, we discuss recent advances in the application of M13 bacteriophage self-assembly structures and the future of this technology.

Keywords:

Biocompatibility, genetic engineering, M-13 bacteriophage, self-assembly.

Affiliation:

Department of Nano Fusion Technology, Pusan National University, Busan 609-735, Republic of Korea; and BIO-IT Foundry Technology Institute, Pusan National University, Busan 609-735.

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